ERN3120 ¨C Molecular, cellular and clinical nutrition

Learning outcome

Knowledge

You will acquire knowledge about:

• Water-soluble vitamins: biochemistry, requirements and recommendations, and links with disease

• Vitamin A: metabolism, role in vision, effects of deficiency, toxicity

• Vitamin D and vitamin K: calcium metabolism, bone biochemistry, rickets, osteomalacia and osteoporosis

• Essential minerals and trace elements: iron metabolism, deficiency and overload; roles of and requirements for Zn, Mg, Se, I, Cr, Cu etc.

• Vitamin E: biochemistry, role in maintaining health; introduction to oxidative damage and antioxidant protection

• Cancer and nutrition: molecular mechanisms of carcinogenesis; DNA damage and repair; nutritional epidemiology of cancer

• Other micronutrients: non-essential components of the diet, with beneficial effects on health

• Food toxicology: principles of toxicology; natural toxins, food mutagens, environmental contaminants of food; risk assessment and management

• Genetic variation and nutrition: genetic elements in common diseases (obesity and diabetes as examples); single nucleotide polymorphisms and responsiveness to diet

• Identifying undernourished patients and patients at risk with regard to nutrition, with the help of nutritional screening.

• The use of different anthropometric methods for monitoring and evaluation of malnutrition; calculation of energy, protein and fluid needs.

• Indications and contraindications for enteral nutrition

• Access routes for enteral nutrition

• The technique for inserting a naso-gastric tube

• Nutrition recommendations and factors that determines the nutritional needs in different population groups such as infants, children, youth, elderly, pregnant, immigrants and vegetarians.

• Factors that influence the need for energy, macro-and micro nutrients, fluids and electrolytes associated with training.

• Nutrition recommendations and needs in patients with cystic fibrosis, Chrohns diseases and different gastrointestinal diseases such as ulcerative colitis, coeliac disease and lactose intolerance

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Skills

You will learn how to

• Read, understand and summarize scientific literature

• Critically assess conflicting evidence and arguments relating to nutritional topics

• Write a dissertation of around 5000 words, based on an individual literature search

• Plan a nutritional intervention trial

• Carry out an experiment to measure DNA damage in lymphocytes. Stain and examine slides from DNA damage experiment and record and analyse results

• Be able to use nutrition screening tools.

• Perform anthropometric measurements including skinfold thickness in patients

• Calculate energy, protein and fluid needs in patients for monitoring of nutrition status.

• Plan and calculate a correct schedule for administration of enteral nutrition

• Assess and evaluate which factors influence the diet for different population groups.

• Assess which factor that influence the nutrition needs in athletes and which factors that influence restitution.

• Evaluate the nutrition needs in patients with cystic fibrosis, Chrohns disease and other gastrointestinal diseases such as ulcerative colitis and coeliac disease and evaluate the complications associated with malnutrition in relation to intestinal function.

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Competence

You will be able to

• Perform self-directed studies based on e-lectures

• Make oral presentations on nutritional topics, based on literature reviews

• Take part in team-based learning, involving close co-operation with colleagues

• Present? controversial topics,

• Write in a scientific style, observing the conventions of a typical journal regarding layout, citations etc.

• Asses and evaluate the nutrition status in patients by the use of nutrition screening tools including skinfold thickness and identify patients at risk and initiate precautions.

• Use different methods to monitor and evaluate malnutrition including calculation of energy, protein and fluid needs.

• Prescribe treatment and prepare a plan to supply enteral nutrition to patients in need of this and implement such a plan.

• Give specific dietary recommendation to different population groups.

• Calculate the nutrient requirements (including energy, macro-and micro nutrients, fluids and electrolytes) for active athletes (including top-level sports athletes).

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• Advice and implement nutritional treatment and follow-up patients with cystic fibrosis, and different gastrointestinal diseases such as ulcerative colitis and coeliac disease.

More about examinations at UiO

• Use of sources and citations
• How to use AI as a student
• Special exam arrangements due to individual needs
• Withdrawal from an exam
• Illness at exams / postponed exams
• Explanation of grades and appeals
• Resitting an exam
• Cheating/attempted cheating

You will find further guides and resources at the web page on examinations at UiO.