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Postdoctoral Fellow
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Affiliation |?Department of Biosciences, UiO
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Short bio
I completed my PhD at the University of Oslo in 2022 with a dissertation titled “LncRNA HOTAIR in human adipose stem cells: transcriptomic and functional characterization”. After that, I moved to Baylor College of Medicine in Houston to work as a postdoctoral fellow for 3 years, in the Department of Cell and Molecular Biology. Currently, I’m a DSTrain MSCA fellow in the Department of Biosciences, working on a collaborative project between two research groups studying chromatin organization in diverse contexts.
Research interests and hobbies
Broadly, I’m interested in the relationship between the form and function of cellular condensates.
In particular, I study condensate dynamics in living cells in response to various cellular stresses. This requires advanced live-cell microscopy and quantitative approaches to probe condensate composition and physical properties. In my previous position I contributed to developing such methods to study condensates in vivo.
In my DSTrain project, I aim to apply these techniques to study how nuclear organization changes when cells are exposed to mechanical stress. Although cells in the human body are constantly exposed to a wide range of mechanical cues, we have a limited understanding of how nuclear architecture adapts to different mechanical environments.
Outside of my research, I enjoy hiking, climbing, and reading.
DSTrain project
The nucleolus under pressure: nucleaolar response to mechanical stress (NorMech)
NorMech explores how physical forces shape the organization and function of the cell nucleus, with a focus on the nucleolus - an essential nuclear condensate involved in protein production and cellular stress responses. In the body, cells constantly experience mechanical forces during processes such as development and migration, yet how these forces influence nuclear organization remains poorly understood. NorMech aims to uncover how changes in the physical environment affect nucleolar behavior and nuclear organization. To answer these questions, we will combine advanced imaging and interdisciplinary expertise in cell and computational biology. This project seeks to uncover new links between mechanics and nuclear function. Ultimately, NorMech will provide insight into how altered cellular mechanics could contribute to human disease and help advance a new direction in nuclear mechanobiology.
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Publications
DSTrain publications
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Previous publications
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